Concomitant weekly cisplatin and altered fractionation radiotherapy in locally advanced head and neck cancer
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چکیده
منابع مشابه
Hyperfractionated accelerated radiotherapy in combination with weekly cisplatin for locally advanced head and neck cancer.
BACKGROUND The purpose of this study was to determine the feasibility and efficacy of hyperfractionated accelerated radiotherapy (HFRCB) combined with simultaneous chemotherapy with weekly cisplatin (CDDP) in locally advanced inoperable head and neck cancer. METHODS From August 1999 to December 2002, 37 patients (median age, 59 years) with Union Internationale Contre le Cancer stage III (n = ...
متن کاملWeekly cisplatin with radiotherapy for locally advanced head and neck squamous cell carcinoma.
PURPOSE Although commonly used for the treatment of locally advanced head and neck squamous cell carcinoma (HNSCC) concomitant radio-chemotherapy (RT-CT) with weekly cisplatin has not been definitely studied. We conducted a single centre retrospective study with the aim to evaluate efficacy and acute toxicity of definitive concomitant RT-CT with 40 mg/m2 weekly cisplatin in patients with locall...
متن کاملpalliative hypofractionated radiotherapy in locally advanced head and neck cancer with fixed neck nodes
background: the locally advanced head and neck cancer with fixed nodes are incurable and has a short survival. this study aims to evaluate the symptom relief, disease response and acute toxicity after palliative hypofractionated radiotherapy. methods: between december 2010 to june 2011, previously untreated 50 patients who had histopathologically proved of head and neck squamous cell carcinoma ...
متن کاملPhase I trial of concomitant hyperfractionated radiotherapy with docetaxel and cisplatin for locally advanced head and neck cancer.
BACKGROUND This study was conducted to determine the maximum tolerated dose of docetaxel when administered concomitantly with radical hyperfractionated radiotherapy and cisplatin in patients with locally advanced head and neck cancer. PATIENTS AND METHODS Patients with stage III-IV tumors received radical radiotherapy of 74.4 Gy given in two daily fractions of 1.2 Gy for 6 weeks. Cisplatin wa...
متن کاملRapid superselective high-dose cisplatin infusion with concomitant radiotherapy for advanced head and neck cancer.
PURPOSE The purpose of this study was to evaluate the efficacy of rapid superselective high-dose cisplatin infusion with concomitant radiotherapy for previously untreated patients with advanced head and neck cancer. METHODS Forty-three patients for whom surgery was contraindicated or who rejected radical surgery were given superselective intra-arterial infusions of cisplatin (100-120 mg/m2/we...
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ژورنال
عنوان ژورنال: Cancer
سال: 2010
ISSN: 0008-543X
DOI: 10.1002/cncr.25189